CLINICAL REFERENCES
References are provided for educational purposes and relate to individual ingredients used in Alpha Shakes™.
| # | Ingredient | Application | Author and Title | Journal Details | Status | Link |
|---|---|---|---|---|---|---|
| 01 | KSM-66 Ashwagandha® | Cognitive Function | Choudhary D, Bhattacharyya S, Bose S. Efficacy and safety of Ashwagandha (Withania somnifera (L.) Dunal) root extract in improving memory and cognitive functions. J Diet Suppl. 2017;14(6):599-612. doi:10.1080/19390211.2017.1284970 |
Journal of Dietary Supplements | published | Study → |
| 02 | KSM-66 Ashwagandha® | Cognitive Function, Energy, and Mood | Kale S, Sarmukkadam S, Swami M, Singh P, Atreya HS. Safety and efficacy of ashwagandha root extract on cognitive functions in healthy, stressed adults: a randomized, double-blind, placebo-controlled study. Cureus. 2024;16(10):e71986. doi:10.7759/cureus.71986 |
Journal of Psychoactive Drugs | published | Study → |
| 03 | KSM-66 Ashwagandha® | Muscle Size, Strength, and Recovery | Wankhede S, Langade D, Joshi K, Sinha SR, Bhattacharyya S. Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial. J Int Soc Sports Nutr. 2015;12:43. doi:10.1186/s12970-015-0104-9 |
Journal of the International Society of Sports Nutrition | published | Study → |
| 04 | KSM-66 Ashwagandha® | Sexual Wellness and Testosterone | Chauhan S, Srivastava MK, Pathak AK. Effect of standardized root extract of ashwagandha (Withania somnifera) on well-being and sexual performance in adult males: a randomized controlled trial. Health Sci Rep. 2022;5(4):e741. doi:10.1002/hsr2.741 |
Health Science Reports | published | Study → |
| 05 | KSM-66 Ashwagandha® | Sexual Wellness and Testosterone | Ambiye VR, Langade D, Dongre S, Aptikar P, Kulkarni M, Dongre A. Clinical evaluation of the spermatogenic activity of the root extract of Ashwagandha (Withania somnifera) in oligospermic males: a pilot study. Evid Based Complement Alternat Med. 2013;2013:571420. doi:10.1155/2013/571420 |
Evidence-Based Complementary and Alternative Medicine | published | Study → |
| 06 | KSM-66 Ashwagandha® | Sleep and Anxiety | Langade D, Kanchi S, Salve J, Debnath K, Ambegaokar D. Efficacy and safety of Ashwagandha (Withania somnifera) root extract in insomnia and anxiety: a double-blind, randomized, placebo-controlled study. Cureus. 2019;11(9):e5797. doi:10.7759/cureus.5797 |
Cureus | published | Study → |
| 07 | KSM-66 Ashwagandha® | Sleep and Anxiety | Langade D, Thakare V, Kanchi S, Kelgane S. Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: a double-blind, randomized, parallel-group, placebo-controlled study. J Ethnopharmacol. 2021;264:113276. doi:10.1016/j.jep.2020.113276 |
Journal of Ethnopharmacology | published | Study → |
| 08 | KSM-66 Ashwagandha® | Sleep and Anxiety | Salve J, Pate S, Debnath K, Langade D. Adaptogenic and anxiolytic effects of ashwagandha roo t extract in healthy adults: a double-blind, randomized, placebo-controlled clinical study. Cureus. 2019;11(12):e6466. doi:10.7759/cureus.6466 |
Cureus | published | Study → |
| 09 | KSM-66 Ashwagandha® | Stress and Anxiety | Chandrasekhar K, Kapoor J, Anishetty S. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med. 2012;34(3):255-262. doi:10.4103/0253-7176.106022 |
Indian Journal of Psychological Medicine | published | Study → |
| 10 | KSM-66 Ashwagandha® | Stress and Anxiety | Choudhary D, Bhattacharyya S, Joshi K. Body weight management in adults under chronic stress through treatment with Ashwagandha root extract: a double-blind, randomized, placebo-controlled trial. J Evid Based Complementary Altern Med. 2017;22(1):96-106. doi:10.1177/2156587216641830 |
Journal of Evidence-Based Integrative Medicine | published | Study → |
| 11 | KSM-66 Ashwagandha® | Stress and Anxiety | Salve J, Pate S, Debnath K, Langade D. Adaptogenic and anxiolytic effects of ashwagandha root extract in healthy adults: a double-blind, randomized, placebo-controlled clinical study. Cureus. 2019;11(12):e6466. doi:10.7759/cureus.6466 |
Cureus | published | Study → |
| 12 | NEM® eggshell membrane collagen | Joint Comfort, Stiffness, and Recovery | Ruff KJ, Morton KM, Duncan SA, Back M. Eggshell membrane (NEM®) reduces exercise-induced joint pain, stiffness and cartilage turnover in healthy men and women: a randomized controlled trial. Int J Phys Med Rehabil. 2024;12:722. doi:10.35248/2329-9096.24.12.722 |
International Journal of Physical Medicine and Rehabilitation | published | Study → |
| 13 | NEM® eggshell membrane collagen | Joint Health | Ruff KJ, DeVore DP, Leu MD, Robinson MA. Eggshell membrane: a possible new natural therapeutic for joint and connective tissue disorders. Results from two open-label human clinical studies. Clin Interv Aging. 2009;4:235-240. |
Clinical Interventions in Aging | published | Study → |
Choudhary D, Bhattacharyya S, Bose S. Efficacy and safety of Ashwagandha (Withania somnifera (L.) Dunal) root extract in improving memory and cognitive functions. J Diet Suppl. 2017;14(6):599-612. doi:10.1080/19390211.2017.1284970
Kale S, Sarmukkadam S, Swami M, Singh P, Atreya HS. Safety and efficacy of ashwagandha root extract on cognitive functions in healthy, stressed adults: a randomized, double-blind, placebo-controlled study. Cureus. 2024;16(10):e71986. doi:10.7759/cureus.71986
Wankhede S, Langade D, Joshi K, Sinha SR, Bhattacharyya S. Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial. J Int Soc Sports Nutr. 2015;12:43. doi:10.1186/s12970-015-0104-9
Chauhan S, Srivastava MK, Pathak AK. Effect of standardized root extract of ashwagandha (Withania somnifera) on well-being and sexual performance in adult males: a randomized controlled trial. Health Sci Rep. 2022;5(4):e741. doi:10.1002/hsr2.741
Ambiye VR, Langade D, Dongre S, Aptikar P, Kulkarni M, Dongre A. Clinical evaluation of the spermatogenic activity of the root extract of Ashwagandha (Withania somnifera) in oligospermic males: a pilot study. Evid Based Complement Alternat Med. 2013;2013:571420. doi:10.1155/2013/571420
Langade D, Kanchi S, Salve J, Debnath K, Ambegaokar D. Efficacy and safety of Ashwagandha (Withania somnifera) root extract in insomnia and anxiety: a double-blind, randomized, placebo-controlled study. Cureus. 2019;11(9):e5797. doi:10.7759/cureus.5797
Langade D, Thakare V, Kanchi S, Kelgane S. Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: a double-blind, randomized, parallel-group, placebo-controlled study. J Ethnopharmacol. 2021;264:113276. doi:10.1016/j.jep.2020.113276
Salve J, Pate S, Debnath K, Langade D. Adaptogenic and anxiolytic effects of ashwagandha roo t extract in healthy adults: a double-blind, randomized, placebo-controlled clinical study. Cureus. 2019;11(12):e6466. doi:10.7759/cureus.6466
Chandrasekhar K, Kapoor J, Anishetty S. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med. 2012;34(3):255-262. doi:10.4103/0253-7176.106022
Choudhary D, Bhattacharyya S, Joshi K. Body weight management in adults under chronic stress through treatment with Ashwagandha root extract: a double-blind, randomized, placebo-controlled trial. J Evid Based Complementary Altern Med. 2017;22(1):96-106. doi:10.1177/2156587216641830
Salve J, Pate S, Debnath K, Langade D. Adaptogenic and anxiolytic effects of ashwagandha root extract in healthy adults: a double-blind, randomized, placebo-controlled clinical study. Cureus. 2019;11(12):e6466. doi:10.7759/cureus.6466
Ruff KJ, Morton KM, Duncan SA, Back M. Eggshell membrane (NEM®) reduces exercise-induced joint pain, stiffness and cartilage turnover in healthy men and women: a randomized controlled trial. Int J Phys Med Rehabil. 2024;12:722. doi:10.35248/2329-9096.24.12.722
Ruff KJ, DeVore DP, Leu MD, Robinson MA. Eggshell membrane: a possible new natural therapeutic for joint and connective tissue disorders. Results from two open-label human clinical studies. Clin Interv Aging. 2009;4:235-240.